Day: October 28, 2020

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of Tetrakis(acetonitrile)copper(I) tetrafluoroborate ([Cu(NCCH3)4]BF4, 3.11 g, 33.0 mmol) and Bis[(2-diphenylphosphino)phenyl]ether (O[C6H4P(C6H5)2]2, DPEphos, 5.33 g, 33.0 mmol) in 300 ml of CH2Cl2 was stirred at room temperature for 3 h. Upon addition of 1,10-Phenanthroline (C12H8N2, phen, 1.78 g, 33.0 mmol) the clear solution turned bright yellow, remained clear, and was stirred for an additional 2 h. Approximately 900 ml of diethyl ether ((CH3CH2)2O) was added to the solution to precipitate a bright yellow solid. The solution containing the newly precipitated solid was then left in the refrigerator for one day. It was vacuum filtered using a medium frit, washed with diethyl ether and dried under vacuum. A bright yellow powder was isolated (yield: 8.00 g, 93 percent)., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Kubi?ek, Katharina; Thekku Veedu, Sreevidya; Storozhuk, Darina; Kia, Reza; Techert, Simone; Polyhedron; vol. 124; (2017); p. 166 – 176;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

To a dichloromethane solution (20cm3) of [PtCl2(PhCN)2] (100 mg, 0.21 mmol), a solution of dppf (118 mg, 0.21 mmol) in dichloromethane was added. The resulting mixture was kept on stirring for 4 hours at room temperature. Solvent was evaporated under reduced pressure and residue was washed thoroughly with hexane followed by diethyl ether to remove excess phosphine. The residue was extracted with dichloromethane, filtered and passed through a Florisil Column. The ensuing solution at room temperature resulted yellow crystals (yield 152 mg, 87percent). Anal. Calcd. for C34H28P2FePtCl2: C, 49.78; H, 3.44percent. Found: C, 49.76; H, 3.46percent. 1H NMR (CDCl3) delta: 4.19 (br, 4H, C5H4), 4.37 (br, 4H, C5H4), 7.37?7.47 (m, Ph), 7.86 (br, Ph), 7.67-7.61 (m, Ph); 31P{1H}NMR (CDCl3) delta?:13.1 [1J(Pt-P) = 3776 Hz] ppm.

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Chauhan, Rohit Singh; Cordes, David B.; Slawin, Alexandra M.Z.; Yadav, Seema; Dash, Chandrakanta; Inorganica Chimica Acta; vol. 478; (2018); p. 125 – 129;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

5931-53-3,5931-53-3, Diphenyl(o-tolyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

EXAMPLE 33 [(2-Methylphenyl)diphenylphosphoranylidene]carbamic acid, ethyl ester A solution of 1.0 g of (2-methylphenyl)diphenylphosphine in 30 ml of ether was treated with 4 ml of 1M ethyl carbonazidate in ether. The mixture was allowed to stand 48 hours, then repeatedly concentrated and finally treated with fresh ether and refrigerated, giving 930 mg of the desired compound, mp 113-114 C.

As the paragraph descriping shows that 5931-53-3 is playing an increasingly important role.

Reference£º
Patent; American Cyanamid Company; US4767749; (1988); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

24171-89-9, Tri(thiophen-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a solution of [Fe2(CO)6{mu-SCH2CH(CH2O2CCH3)S}] (0.044?g, 0.1?mmol) and tris(2-furyl)phosphine (0.023?g, 0.1?mmol) in CH2Cl2 (5?mL) was added a solution of Me3NO¡¤2H2O (0.011?g, 0.1?mmol) in MeCN (5?mL). The mixture was stirred at room temperature for 1?h and then the solvent was reduced on a rotary evaporator. The residue was subjected to TLC separation using CH2Cl2/petroleum ether?=?1:1 (v/v) as eluent. From the main red band, 0.062?g (95%) of complex 2 was obtained as a red solid., 24171-89-9

24171-89-9 Tri(thiophen-2-yl)phosphine 90384, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Chen, Fei-Yan; He, Jiao; Mu, Chao; Liu, Xu-Feng; Li, Yu-Long; Jiang, Zhong-Qing; Wu, Hong-Ke; Polyhedron; vol. 160; (2019); p. 74 – 82;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

932710-63-9, 4-(Di-tert-butylphosphino)-N,N-dimethylaniline is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

932710-63-9, The procedure used to prepare 1a was modified by replacing the HgCl2 addition with 0.036 g (0.1 mmol) HgBr2. After 1 week,yellow crystals suitable for X-ray analysis were obtained. Yield:0.036 g, 51% based on Hg(SePh)2.Properties: yellow crystalline substance. Melting point: 183-185C. Anal. Calc. for C44H66Hg2Br2N2P2Se2 (1403.84): Hg, 28.58;Se, 11.25; C, 37.64; H, 4.74; N, 2.00. Found: Hg, 28.54; Se, 11.21;C, 37.58; H, 4.60; N, 1.93%. IR (KBr): 3043 [vs(CAH)]; 2960[vas(CH3)]; 2867 [vs(CH3)]; 1598, 1476, 1447 [vs(CC)]; 1372[v(CAN)]; 1070, 1024 [dip(CCAH)]; 741, 694 [dop(CCAH)]; 509[v(PAC)]; 468 cm1 [dop(CCAC)] (dip and dop = in-plane and outof-plane bending motions, respectively).

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

Reference£º
Article; Stieler, Rafael; Faoro, Eliandro; Cechin, Camila Nunes; Floriano, Luana; Lang, Ernesto Schulz; Journal of Molecular Structure; vol. 1079; (2014); p. 9 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1608-26-0,N,N,N’,N’,N”,N”-Hexamethylphosphinetriamine,as a common compound, the synthetic route is as follows.

General procedure: A mixture of the aminobenzamidine 1 (5.0 mmol) andtris (dimthylamino) phosphine (5.0 mmol) dissolved in anhydroustoluene (10 mL) were heated under reflux for 48 h.After evaporating the solvent in vacuum, the resulting solidproduct was recrystallized from CCl4 (2b, 2d) or alternativelythe obtained oil (2a, 2c) was purified by columnchromatography using silica gel (60-120 mesh) with ethylacetate: petroleum ether (4 : 6) as eluant.

1608-26-0, 1608-26-0 N,N,N’,N’,N”,N”-Hexamethylphosphinetriamine 15355, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Hichri, Sarra; Abderrahim, Raoudha; Letters in Organic Chemistry; vol. 13; 4; (2016); p. 289 – 292;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

General procedure: Fe2(CO)6(mu-edt) (1) (100 mg, 0.268 mmol), Me3NO(21 mg, 0.280 mmol) and dppm (104 mg, 0.271 mmol) were heated in boiling acetonitrile (15 mL) for 30 min. After cooling to room temperature, the volatiles were removed under reduced pressure and the residue chromatographed by TLC on silica gel. Elution with hexane/CH2Cl2 (7:3, v/v) developed two bands. The faster-moving band afforded Fe2(CO)5(kappa1-dppm)(mu-edt) (3) (135 mg,69 percent) as red crystals, while the slower-moving band gave Fe2(CO)4(mu-dppm)(mu-edt) (4) [23] (17 mg, 9 percent) as red crystals after recrystallization from hexane/CH2Cl2 at 4 C., 12150-46-8

12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Rana, Shahed; Ghosh, Shishir; Hossain, Md. Kamal; Rahaman, Ahibur; Hogarth, Graeme; Kabir, Shariff E.; Transition Metal Chemistry; vol. 41; 8; (2016); p. 933 – 942;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

787618-22-8,787618-22-8, Dicyclohexyl(2′,6′-diisopropoxy-[1,1′-biphenyl]-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Palladium reagents were synthesized following the scheme of Figure 14 for generalprocedure A. In a nitrogen-filled glovebox, an oven-dried scintillation vial (1 0 mL), whichwas equipped with a magnetic stir bar and fitted with a Teflon screwcap septum, vascharged with RuPhos (2.5 equiv), a dihaloaryl compound (1 equiv) and cydohexane (1.2mL). Solid [(1,5-COD)Pd(CH2Si:Me3)] (2.5 equiv) was added rapidly in one portion and theresulting solution vvas stirred for 16 hat Jt. After this time, pentane (3 mL) was added andthe resulting mixture vas placed into a -20 C freezer for 3 h. The vial was then takenoutside of the glove box, and the resulting precipitate was filtered, washed with pentane (3 X3 mL), and dried under reduced pressure to afford the oxidative addition complex (Figure14)

As the paragraph descriping shows that 787618-22-8 is playing an increasingly important role.

Reference£º
Patent; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; BUCHWALD, Stephen, L.; PENTELUTE, Bradley, L.; ZHANG, Chi; (170 pag.)WO2017/151910; (2017); A2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

564483-19-8, Di-tert-butyl(2′,4′,6′-triisopropyl-[1,1′-biphenyl]-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

564483-19-8, tBuXPhos (232 mg, 0.546 mmol) was added inone portion at -78C to a solution of ketone 1 (192 mg, 0.546mmol) in CH2Cl2 (5mL) and the resulting slurry allowed to warmto r.t. while it was stirred. The solvent was then removed undervacuum and the crude product washed with MeOH to afford 7as a white solid (321 mg, 76%).

As the paragraph descriping shows that 564483-19-8 is playing an increasingly important role.

Reference£º
Article; Ines, Blanca; Holle, Sigrid; Bock, Dominique A.; Alcarazo, Manuel; Synlett; vol. 25; 11; (2014); p. 1539 – 1541;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24171-89-9,Tri(thiophen-2-yl)phosphine,as a common compound, the synthetic route is as follows.

A CH2Cl2 solution (30 mL) of [Fe3(CO)12] (200 mg, 0.40 mmol) and PTh3 (111 mg, 0.40 mmol) was heated to reflux for 12 h. The solvent was removed under reduced pressure and the residue chromatographed by TLC on silica gel. Elution with hexane/CH2Cl2 (v/v 9:1) developed two bands [Fe2(CO)6(mu-eta1,eta2-Th)(mu-PTh2)] (3) (160 mg, 72%) as light orange crystals and [Fe2(CO)5(mu-eta1,eta2-Th)(mu-PTh2)(PTh3)] (4) (6 mg, 2%) as deep orange crystals., 24171-89-9

The synthetic route of 24171-89-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Conference Paper; Rahaman, Ahibur; Alam, Fakir Rafiqul; Ghosh, Shishir; Haukka, Matti; Kabir, Shariff E.; Nordlander, Ebbe; Hogarth, Graeme; Journal of Organometallic Chemistry; vol. 730; (2013); p. 123 – 131;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate