With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-19-5,Tricyclohexylphosphine oxide,as a common compound, the synthetic route is as follows.
Ce(NO3)4(Cy3PO)2 An excess of CAN (0.45 g 0.82 mmol) in2.5 mL water were stirred with a solution of Cy3PO (0.24 g0.81 mmol) in 1.8 mL of chloroform for 10 minutes. The orangechloroform layer was separated, dried (MgSO4), filtered and mixedwith an equal volume of diethylether. Cooling to -30 C gave yellowneedles suitable for X-ray crystallography (0.19 g 46% based onCy3PO). Analysis (%) Expected (found): C 44.08 (44.92) H6.78 (6.73)N 5.71 (5.69).
13689-19-5, 13689-19-5 Tricyclohexylphosphine oxide 26187, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Article; Coles, Simon J.; Fieldhouse, Sarah J.; Klooster, Wim T.; Platt, Andrew W.G.; Polyhedron; vol. 161; (2019); p. 346 – 351;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate