4020-99-9, Methoxydiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
cis-RuC12(slMes)(phenylindenylidene)(Ph2P(OMe)), cis-C885: trans-C748? 2Py (27.18 g, 30 mmol) was placed in a round-bottomed flask with a magnetic stir bar under nitrogen, to which degassed heptanes were added (5000 mL). Phosphinite Ph2P(OMe) (6.8 g, 31.5 mmol) was added via syringe. The reaction vessel was evacuated and refilled with N2 (3x). The mixture was stirred under N2 for 1 hr at ambient temperature (20 – 25 C). because there was some undissolved starting material, degassed CH2C12 (250 mL) was added and all solids were dissolved. The solution was passed through a silica plug (2.5? x 1.5?, D X H) and CH2C12 was used as eluent to remove the first red band of material, which was trans-C885. Then EtOAc was used as eluent to remove a second band that was concentrated and filtered providing brown crystals of cis-C885 (8.49 g). ?H NMR (400 MHz, CD2C12, ppm): oe 8.78 (dd, J = 8 Hz, J = 1 Hz, 1H), 7.52-7.24 (m, 8H), 7.13 – 6.89 (m, 9H), 6.75 (m, 2H), 6.43 (s, 1H), 6.40 (s, 1H), 6.24 (s, 1H), 6.11 (s, 1H), 3.98-3.63 (m, 4H), 3.66 (d, J = 10 Hz, 3H), 2.79 (s, 3H), 2.56 (s, 3H), 2.54 (s, 3H), 2.21 (s, 3H), 1.95 (s, 3H),1.66 (s, 3H). 3?P NIVIR (161.8 MHz, CD2C12, ppm): oe 133.3 (s), 4020-99-9
As the paragraph descriping shows that 4020-99-9 is playing an increasingly important role.
Reference£º
Patent; MATERIA, INC.; GIARDELLO, Michael, A.; TRIMMER, Mark, S.; WANG, Li-Sheng; DUFFY, Noah, H.; JOHNS, Adam, M.; RODAK, Nicholas, J.; FIAMENGO, Bryan, A.; PHILLIPS, John, H.; (127 pag.)WO2017/53690; (2017); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate