With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1608-26-0,N,N,N’,N’,N”,N”-Hexamethylphosphinetriamine,as a common compound, the synthetic route is as follows.
Under nitrogen protection, Weigh 2g of compound 5 in a 50mL dry two-necked bottle, Add 15 mL of dry toluene, Slowly add 0.7 mL of tris(dimethylamino)phosphine, Reflux for 4 h. The solvent was removed under reduced pressure. The crude product is separated by a column, I got 1.96g of compound J, Yield 86%, 1608-26-0
The synthetic route of 1608-26-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Shanghai Jiao Tong University; Cui Yong; Chen Xu; Liu Yan; (21 pag.)CN108586529; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate