With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.
The solutions of a (0.0256 g, 0.1 mmol) ofH2dz in 10 cm3 of methanol, (0.1 mmol, 0.0273 g) ofCoCl2.6H2O in a10 cm3 of methanol) and (0.0554 g,0.1 mmol of 1,1′-bis(diphenylphosphine) ferrocene(dppf) were mixed and refluxed at 55 oC for 2 h togive brown colored precipitate and the solutionswas filtered and finally it was dried in an openair. Yield= 76percent, d.p= 288¡ãC. Anal. Calc.percent for C47H41 Cl N4 P2 Co S Fe:C, 62.30; H, 4.56; N, 6.18,S, 3.54, Co, 6.50, Cl, 3.91. Found percent: C, 61.95; H,4.62; N, 6.48, S; 3.85, Co; 6.73,Cl, 4.01. 1H-NMR(d6-DMSO) delta:7.78(4H,d), 7.42(4H,t), 7.28 ? 7.38(mH), 11.61(1H). The Proposed GeometricalStructure shown in Figure 1.
12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Article; Mohamad, Hikmat Ali; Oriental Journal of Chemistry; vol. 34; 4; (2018); p. 1919 – 1925;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate