With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4020-99-9,Methoxydiphenylphosphine,as a common compound, the synthetic route is as follows.
As shown in Figure 1 Wittig reagent between methoxy benzyldiphenyloxy phosphate synthesis route.In a 1000 ml reaction flask, 108 g was added(0.5 mol) of diphenylmethoxyphosphine(Purity & gt; 99.5%) and 120 g (0.7 mol)M-methoxybenzyl chloride (content ? 99.2%),Stirring temperature conditions to 55 , and at this temperature for 8 hours, Paul finished cooling to 10 , directly into the next step reaction.
4020-99-9, 4020-99-9 Methoxydiphenylphosphine 77636, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Patent; Taicang Kastem New Material Co., Ltd; Li, Ruiqing; (5 pag.)CN105440075; (2016); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate