With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13885-09-1,2-(Diphenylphosphino)biphenyl,as a common compound, the synthetic route is as follows.
1.453 g of 2-diphenylphosphine-biphenyl, 1.404 g of 2-iodoanisole, 122.5 mg of cymene dichloride dimer, and 78.7 mg of N-Ac-beta-alanine were added to the reactor. 1.536 g of cesium acetate and 2 mL of toluene, the reaction temperature was controlled at 120 ¡ã C for 18 hours, then cooled to room temperature, filtered through celite and distilled under reduced pressure to give 1.76 g of product.95percent.
13885-09-1, 13885-09-1 2-(Diphenylphosphino)biphenyl 12976978, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Patent; Hubei University; Liu Yuejin; Li Jiawei; Wang Liangneng; Zeng Minghua; (9 pag.)CN109400646; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate