With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.
50777-76-9, 0.32 g (1.61 mmol) of the compound [1], 0.47 g (1.61 mmol) of 2- (diphenylphosphino) benzaldehyde, 1.5 g (1.61 mmol) of Amberlyst 15 (0.11 g), 15 mL of toluene were added, and the mixture was allowed to react at 80 ¡ã C. for 8 hours. The reaction solution was filtered, and the filtrate was evaporated under reduced pressure to give 0.61 g (yield: 80percent) of the target compound (hereinafter referred to as the compound [3]) represented by the following formula [3].
The synthetic route of 50777-76-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Mitsui Chemicals; Ishii, Seiichi; Ichikawa, Shinichiro; Fujita, Otomo Toshinori; (49 pag.)JP2018/162230; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate