18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Under inert gas protection conditions,To a flask equipped with a stirring magnet, 344 mg of Fe2S2(CO)6 (1 mmol) and 30 mL of tetrahydrofuran solvent were added.A dark red solution was obtained, and the resulting solution was cooled to -78 ¡ã C with a liquid nitrogen bath.2.1 mL of lithium triethylborohydride (1M in THF) solution was slowly added under stirring.After reacting for 15 min, 0.2 mL of trifluoroacetic acid (2.5 mmol) was added and the reaction was continued for 15 min.Add 348 mg of P(C6H4-4-F)3 (1.1 mmol), stir at room temperature for 3 h before adding788 mg of I-4-C6H4N(CH2Cl)2 (2.5 mmol) and 0.3 mL of triethylamine were stirred at room temperature for 12 h.The solvent of tetrahydrofuran was removed by rotary distillation, and the residue was extracted with dichloromethane, and then subjected to thin-layer chromatography using a solvent of dichloromethane/petroleum ether ratio of 1:5 to collect a main color band to obtain a model 2 .
18437-78-0, 18437-78-0 Tris(4-fluorophenyl)phosphine 140387, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Patent; Sichuan University of Science and Engineering; Li Yulong; He Jiao; Wu Yu; Xie Ying; Jiang Jin; Sun Yanchun; Wang Zheng; Zou Like; Xie Bin; Gao Fan; Mu Chao; (11 pag.)CN109232665; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate