24171-89-9, Tri(thiophen-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2,6-Bis(chloromethyl)-3-hydroxypyridine hydrochloride (5) (0.20 g, 0.88 mmol) was added to a solution of tris(2-thienyl)phosphine (0.98 g, 3.50 mmol) in acetonitrile (40 mL) and the mixture was refluxed for 48 h. Then, the solvent was evaporated in vacuo, the dry residue was dissolved in chloro- form and washed with water. The aqueous filtrate was dried in vacuo, and recrystallized from acetone. The yield was 0.10 g (15%), a white crystalline compound, m.p. 176-178 C. 1H NMR (DMSO-d6), d: 5.00 (d, 2 H, CH2P, J = 15.3 Hz); 5.11 (d, 2 H, CH2P, J = 15.7 Hz); 7.10, 7.34 (AB-system, 2 H, PyH, J = 8.4 Hz); 7.47-7.49 (m, 3 H, P(2-thien)3); 7.51-7.53 (m, 3 H, P(2-thien)3); 7.89 (dd, 3 H, P(2-thien)3, J1= 8.3 Hz, J2= 3.6 Hz); 7.97 (dd, 3 H, P(2-thien)3, J1= 8.3 Hz, J2= 3.6 Hz); 8.47-8.50 (m, 6 H, P(2-thien)3); 11.33 (s, 1 H, OH). 13C NMR (DMSO-d6), d: 20.92 (s, CH2P); 25.93 (d, CH2P, J = 54.4 Hz); 119.25 (d, Cthien, J = 86.5 Hz); 123.89 (s, CPyr); 124.71 (s, CPyr); 129.64 (d, Cthien, J = 13.4 Hz); 131.00 (d, Cthien, J = 10.1 Hz); 133.74 (d, Cthien, J = 10.2 Hz); 135.23 (d, Cthien, J = 2.1 Hz); 137.02 (s, CPyr); 138.01 (CPyr); 139.45 (d, Cthien, J = 12.7 Hz); 153.09 (t, CPyr, J = 5.1 Hz). 31P NMR (DMSO-d6), d: 4.07; 4.31. HRMS, found: m/z 340.4863 [M – 3 Cl – H]2+. C31H26NOP2S6Cl2. Calculat- ed: [M – 3 Cl – H] = 340.4863., 24171-89-9
As the paragraph descriping shows that 24171-89-9 is playing an increasingly important role.
Reference£º
Article; Shtyrlin; Vafina; Pugachev; Khaziev; Nikitina; Zeldi; Iksanova; Shtyrlin, Yu. G.; Russian Chemical Bulletin; vol. 65; 2; (2016); p. 537 – 545; Izv. Akad. Nauk, Ser. Khim.; 2; (2016); p. 537 – 545,9;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate