With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.719-80-2,Ethoxydiphenylphosphine,as a common compound, the synthetic route is as follows.
719-80-2, Ethyl diphenylphosphinite,0.87 g (0.0038 mol), was added dropwise to asolution of 1.25 g (0.0038 mol) of compound 21a in1 mL of diethyl ether on cooling to -5 to 5C. Themixture was left to stand for 24 h at room temperature,and the solvent and volatile components were removedunder reduced pressure. Yield 1.44 g (76.6%), colorlesscrystals, mp 146-148C (from isooctane). The spectralcharacteristics of samples of 23a synthesized bydifferent methods were identical.
The synthetic route of 719-80-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Gazizov; Ivanova, S. Yu.; Khairullin; Kirillina, Yu. S.; Gazizova; Russian Journal of General Chemistry; vol. 88; 11; (2018); p. 2243 – 2250; Zh. Obshch. Khim.; vol. 88; 11; (2018); p. 1761 – 1769,9;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate