Day: September 24, 2020

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The solution of dppf (1.6632g, 3mmol)in 15ml CH2Cl2 was added to a solution of PdCl2(0.5320g, 3mmol) that dissolved in 2 cm3 ethanoland 2 cm3 concentrate HCl. The mixture was reuxfor 3 hrs. And then the solvent was evaporate at roomtemperature to give red precipitate. A small portion ofthis complex was dissolve in CH2Cl2 and set to slowevaporation at room temperature after a few days, thered colored needle crystals were formed suitable forsingle-crystal diffraction analysis15. The melting pointis 253¡ãC, yield is 2.086gm (95percent), formula: [Pd(k2-dppf)Cl2] and M.wt.is 816.58 gm/mole, as shown inFigure 1.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Ali, Karwan Omer; Mohammad, Hikmat Ali; Gerber, Thomas; Hosten, Eric; Oriental Journal of Chemistry; vol. 33; 2; (2017); p. 584 – 592;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 0.0381 g CuI (0.2 mmol), 0.0464 g dpq (0.2 mmol) and 0.1077 g pop (0.2 mmol) were dissolved in the mixed solvents of 5 mL CH3OH and 5 mL CH2Cl2 at room temperature. The insoluble residues were removed by filtration, and the filtrate was evaporated slowly at room temperature for several days until yellow crystalline products have been obtained. Yield: 75%. Anal. Calc.for C50H36CuIN4OP2: C, 58.07; H, 4.31; N, 6.30. Found: C, 58.39;H, 3.92; N, 6.50%. 1H NMR (600 MHz, DMSO, 298 K): delta, ppm:6.66-7.42 (m, pop-aromatic ring), 7.99-9.53 (m, dpq-heteroaromaticring); 31P NMR (600 MHz, DMSO, 298 K): delta, ppm: 11.63(s, pop). IR for 7 (KBr pellets, cm-1): 3435(vs), 3052(w), 1585(w),1435(vs), 1386(m), 1214(m), 1096(w), 805(w), 739(s), 697(s),512(m), 440(w)., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Kuang, Xiao-Nan; Lin, Sen; Liu, Jian-Ming; Han, Hong-Liang; Liu, Min; Xin, Xiu-Lan; Yang, Yu-Ping; Li, Zhong-Feng; Jin, Qiong-Hua; Li, Si-Fan; Li, Yue-Xue; Feng, Yue-Bing; Polyhedron; vol. 165; (2019); p. 51 – 62;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

7650-91-1,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7650-91-1,Benzyldiphenylphosphine,as a common compound, the synthetic route is as follows.

1. “A”REACTION. BENZYIDIPHENYLPHOSPHINE (APPROXIMATELY 1. 0 G or 3.6 mmol ; Strem CHEMICALS), IrCI3* nH2O (APPROXIMATELY 0.52 g or 1.7 mmol ; available from Johnson Matthey Inc. of West DEPTFORD, NEW Jersey), and ethoxyethanol (approximately 15 ml ; ALDRICH, degassed) can be stirred at approximately 130C for approximately 45 minutes under nitrogen. The yellow precipitate may be isolated by filtration and dried under vacuum to yield approximately 0.78 g of the intermediate product. 31P NMR (202 MHz, CD2CI2, 296 K): -38.83. 2. “B”reaction. The product from the A reaction (approximately 0.30 g) can be combined with the sodium salt of 2,4-pentanedione (approximately 0.59 g or 0.48 mmol ; prepared from the corresponding acid and sodium hydride (both from ALDRICH)) and 2-ethoxyethanol (approximately 15 mL; ALDRICH), and the contents can be stirred under nitrogen at approximately 130C for approximately one hour. The volatile components can then be removed in vacuo, and the product may be purified from the resulting crude off-white solid via silica gel flash chromatography with CH2CI2 as the eluting solvent. The product (approximately 35 mg) may be isolated as a white solid that exhibits blue luminescence under 254 and 365 nm illumination. 31P NMR (202 MHz, CD2CI2, 296 K): -5.28.

The synthetic route of 7650-91-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; E.I. du Pont de Nemours and Company; WO2004/16710; (2004); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A dichloromethane solution of [Fe3(mu3-YTe)(CO)9] {Y = S (1), Se(2), Te(3)} (0.1 mmol) was reacted with bis-(diphenylphosphino) ferrocene (55 mg, 0.1 mmol) at room temperature under continuous stirring condition and nitrogen atmosphere for 3 h. The reaction was monitored by TLC. On completion of the reaction the solution was dried under vacuum and the residue was dissolved in dichloromethane solvent and subjected to chromatographic work-up using preparative TLC. Elution with dichloromethane/hexane (30:70 v/v) solvent mixture separated a red compound, [Fe3YTe(CO)8{eta2-(PPh2)(C5H4)Fe(C5H4)(PPh2)}] {Y = S (8), Se(9), Te(10)} (Yields = 62 mg, 56percent (8), 70 mg, 61percent (9), 86 mg, 72percent (10)) along with unreacted [Fe3YTe(CO)9] and trace amount of a black product and decomposition during the work-up.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Tirkey, Vijaylakshmi; Boddhula, Rajkumar; Mishra, Sasmita; Mobin, Shaikh M.; Chatterjee, Saurav; Journal of Organometallic Chemistry; vol. 794; (2015); p. 88 – 95;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13360-92-4,Phenoxydiphenylphosphine,as a common compound, the synthetic route is as follows.

EXAMPLE 20 Diphenyl[1-(morpholinosulfonylamino)ethyl]phosphine oxide. EQU27 When a mixture of equimolar quantities of phenyl diphenylphosphinite, acetaldehyde, and morpholinosulfonylamine in chlorobenzene is treated by the procedure used in the preceding experiment, the product is a white solid, mp 215-217C., 31 P nmr (DMSO-d6) -30.9 ppm., 13360-92-4

The synthetic route of 13360-92-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Monsanto Company; US3954860; (1976); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13440-07-8,Di(naphthalen-1-yl)phosphine oxide,as a common compound, the synthetic route is as follows.

4-fluorophenylacetylene (0.060 g, 0.5 mmol) was added to the reaction flask.Dinaphthylphosphorus (0.30 g, 1 mmol),CuSCN (0.012 g, 0.1 mmol),Tert-butyl alcohol peroxide (0.45 mL, 3 mmol) and toluene (2 mL),90oC reaction;TLC tracks the reaction until it is completely over;The crude product obtained after the completion of the reaction was separated by column chromatography (ethyl acetate: petroleum ether = 1:1) to give the desired product.(Yield 82%)., 13440-07-8

13440-07-8 Di(naphthalen-1-yl)phosphine oxide 23110917, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Nantong Textile Silk Industrial Technology Institute; Soochow University (Suzhou); Zou Jianping; Tao Zekun; Lv Shuaishuai; Li Chengkun; Li Jianan; (12 pag.)CN109096336; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.855-38-9,Tris(4-methoxyphenyl)phosphine,as a common compound, the synthetic route is as follows.,855-38-9

Using PHEMA-TX-1 as catalyst, the tris(4-methoxyphenyl)phosphane(1a) was transformed into tris(4-methoxyphenyl)phosphineoxide (2a) (Scheme 6). Typically, 1a (352 mg, 1.0 mmol), PHEMA-TX-1(0.52 mg, 0.001 mmol, 19 muL stock solution prepared by dissolving 56 mg PHEMA-TX-1 in 2.0 mL of DMF), CH3OH (30 mL) were addedinto to a 100 mL round bottom flask equipped with a magnetic stirrer.The reaction was triggered by irradiation of a 23W house hold lamp at room temperature under air atmosphere. The photocatalytic reaction was monitored by TLC (eluent: petroleum ether/ethyl acetate=20/1)and finished after 8 h. The solution was concentrated under vacuum and the mixture was again dissolved in 5 mL of ethyl acetate (EA). ThePHEMA-TX-1 was precipitated in EA and recovered for the second cycle of photocatalytic reaction. The NMR yield of 2a in the first cycle was 99% as determined by 1H NMR analysis of the crude reaction mixtureusing dibromomethane as internal standard. Subsequently, using the recovered PHEMA-TX-1 as catalyst, the following cycles of reactionswere performed using the same procedure as above. The result wasshown in Scheme 6. 1H NMR (400 MHz, CDCl3) delta 7.57 (dd, J=9.4,9.4 Hz, 6H), 6.95 (d, J=8.0 Hz, 6H), 3.83 (s, 9H).

The synthetic route of 855-38-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ding, Aishun; Chen, Yang; Wang, Guowei; Zhang, Yaopeng; Hu, Jianhua; Guo, Hao; Polymer; vol. 174; (2019); p. 101 – 108;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.719-80-2,Ethoxydiphenylphosphine,as a common compound, the synthetic route is as follows.

719-80-2, Ethyl diphenylphosphinite,0.87 g (0.0038 mol), was added dropwise to asolution of 1.25 g (0.0038 mol) of compound 21a in1 mL of diethyl ether on cooling to -5 to 5C. Themixture was left to stand for 24 h at room temperature,and the solvent and volatile components were removedunder reduced pressure. Yield 1.44 g (76.6%), colorlesscrystals, mp 146-148C (from isooctane). The spectralcharacteristics of samples of 23a synthesized bydifferent methods were identical.

The synthetic route of 719-80-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Gazizov; Ivanova, S. Yu.; Khairullin; Kirillina, Yu. S.; Gazizova; Russian Journal of General Chemistry; vol. 88; 11; (2018); p. 2243 – 2250; Zh. Obshch. Khim.; vol. 88; 11; (2018); p. 1761 – 1769,9;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6372-42-5,Cyclohexyldiphenylphosphine,as a common compound, the synthetic route is as follows.,6372-42-5

0.86 g (2.30×10″3 moles) of trichlorotris(tetrahydrofuran)vanadium [VCI3(THF)3], 20 ml of toluene and, subsequently, 2.40 g (9.0×10″3 moles) of dipheny(cyclohexyl)phosphine (P/V molar ratio = 4) were placed into a 100 ml tailed flask. The mixture obtained was left, under vigorous stirring, at room temperature, for 60 minutes and, then, heated under reflux for 1 hour. The suspension obtained was filtered in the hot (60C) and the fraction collected was concentrated, under vacuum, at room temperature. Subsequently, drop by drop, under stirring, about 50 ml of pentane were added, obtaining the precipitation of a dark powder. After about 3 hours, everything was filtered and the solid light blue/gray residue obtained was washed with pentane (50 ml) and dried, under vacuum, at room temperature, obtaining 1.30 g (conversion with respect to starting [VCI3(THF)3] = 81.4%) of complex VCI3(PCyPh2)2 (molecular weight = 693.97 gxmol”1). (0157) Elementary analysis [found (calculated)] C: 62.40% (62.31%); H: 6.30% (6.10%); CI: 15.50% (15.33%); P: 9.0% (8.93%); V: 7.20% (7.34%)

As the paragraph descriping shows that 6372-42-5 is playing an increasingly important role.

Reference£º
Patent; VERSALIS S.P.A.; RICCI, Giovanni; LEONE, Giuseppe; SOMMAZZI, Anna; FORNI, Alessandra; MASI, Francesco; (110 pag.)WO2016/128812; (2016); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24171-89-9,Tri(thiophen-2-yl)phosphine,as a common compound, the synthetic route is as follows.

To a solution of the chloro derivative of pyridoxine 9 (1 equiv) in 30 ml of acetonitrile were added trisubstituted phosphine (1-5 equiv). The reaction mixture was refluxed for 7 h. Different workup procedures were used for preparation of phosphonium salts., 24171-89-9

As the paragraph descriping shows that 24171-89-9 is playing an increasingly important role.

Reference£º
Article; Pugachev, Mikhail V.; Shtyrlin, Nikita V.; Sapozhnikov, Sergey V.; Sysoeva, Lubov P.; Iksanova, Alfiya G.; Nikitina, Elena V.; Musin, Rashid Z.; Lodochnikova, Olga A.; Berdnikov, Eugeny A.; Shtyrlin, Yurii G.; Bioorganic and Medicinal Chemistry; vol. 21; 23; (2013); p. 7330 – 7342;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate