With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7650-91-1,Benzyldiphenylphosphine,as a common compound, the synthetic route is as follows.
General procedure: The following procedure was used in place of the general procedure for this reaction: SiO2 (0.0561 g) and di-(mu-acetato)bis-{2-[(N,N-dimethylamino)methyl]phenyl-C,N}dipalladium(II) 1a (0.0222 g, 0.0370 mmol) were mixed first in a small round-bottomed flask. A stir bar was inserted and the flask, septum, and stirring spatula were all transferred to a glove box with an atmosphere of N2. Benzyldiphenylphosphine 7 (0.020 g, 0.072 mmol) was then added to the flask and thoroughly mixed with the spatula. The reaction was allowed to stir at room temperature in the glove box. The flask was capped with the septum before being removed from the glove box and put in a preheated oil bath (100 C) for 2 h. No CaCl2-filled syringe was used in this reaction. The reaction mixture was filtered into a flask with LiCl as described in the general procedure and purified using preparative TLC in CH2Cl2., 7650-91-1
7650-91-1 Benzyldiphenylphosphine 603920, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Article; Lamb, Jessica R.; Stepanova, Valeria A.; Smoliakova, Irina P.; Polyhedron; vol. 53; (2013); p. 202 – 207;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate