With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.
A mixture of CuI (0.0379g, 0.2mmol), POP (0.1080g, 0.2mmol) and C16H6N6 (0.0565g, 0.2mmol) were dissolved in a mixture of CH2Cl2 (5ml) and CH3OH (5ml), stirred for 6h and filtered. Yellow crystals of 4 were obtained from the filtrate after standing at room temperature for several days. Yield: 85percent. Anal. Calc. for C52H34CuIN6OP2: C, 61.71; H, 3.36; N, 8.31. Found: C, 60.97.11; H, 3.88; N, 7.70percent. IR (cm?1): 3399m, 3050w, 1585w, 1512w, 1461m, 1433m, 1372s, 1259m, 1209s, 1095m, 997w, 873w, 804w, 748s, 697s, 619w, 512s, 425m. 1H NMR (600MHz, CDCl3, 298K) delta, ppm: 7.1?7.4 (m, overlap with the solvent peak signal, C16H6N6-aromatic ring, pop-aromatic ring), 8.6 (d, 2H, C16H6N6-aromatic ring), 8.0 (d, 2H, C16H6N6-aromatic ring)., 166330-10-5
The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Zhang, Yan-Ru; Yu, Xiao; Lin, Sen; Jin, Qiong-Hua; Yang, Yu-Ping; Liu, Min; Li, Zhong-Feng; Zhang, Cun-Lin; Xin, Xiu-Lan; Polyhedron; vol. 138; (2017); p. 46 – 56;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate