6372-42-5, Cyclohexyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,6372-42-5
General procedure: A 20mL scintillation vial was charged with 1equiv of NCr(NiPr2)2I (1) [42], 110 acetonitrile (3mL), and a Teflon-coated stir bar. This mixture was stirred at room temperature giving a dark red-orange solution. Separately, a solution of 111 AgSbF6 (1equiv) was prepared in acetonitrile (1-2mL). The AgSbF6 solution was then added dropwise to the stirred solution of 1. Upon addition, copious amounts of off-white precipitate formed, and the solution became dark brown. The resultant mixture was stirred for 20min after complete addition of the Ag solution. The mixture was then filtered over Celite to remove the precipitate. The dark brown solution of 2 collected was once again stirred at room temperature and a solution of PR3 (1-2equiv) in acetonitrile (1-2mL) was added. (1equiv of the phosphine was used if it was a solid or high-boiling liquid phosphine that is difficult to remove by recrystallization. 2equiv of phosphine were used if PR3 is a low-boiling liquid easily removed in vacuo.) Upon addition of PR3, the solution quickly became yellow-orange. The reaction solution was stirred for 1h at room temperature. The volatiles were then removed in vacuo to give a dark residue. This residue was rinsed with small aliquots of cold Et2O (3¡Á1mL) to remove any unreacted 1. The residue was once more dried in vacuo. The residue was dissolved in a minimal amount of CH2Cl2 or CHCl3 and layered with Et2O or pentane. The layered solution was then stored overnight at -35C to yield yellow-orange X-ray quality crystals.
6372-42-5 Cyclohexyldiphenylphosphine 80756, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Article; Aldrich, Kelly E.; Billow, Brennan S.; Staples, Richard J.; Odom, Aaron L.; Polyhedron; vol. 159; (2019); p. 284 – 297;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate