With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.146960-90-9,1,1′-Bis(dicyclohexylphosphino)ferrocene,as a common compound, the synthetic route is as follows.
1,1′-Bis(dicyclohexylphosphino)ferrocene (dcpf) (0.578 g, 1.0 mmol) was added to a solution of gold(I) cyanide (0.223 g, 1.0 mmol) in 30 mL CH3OH:CH2Cl2 (50:50 V/V) mixture at room temperature. The resultant suspension was refluxed with stirring under nitrogen atmosphere for 24 h. Slowly, the colour of the solution changed from light yellowish orange to dark yellowish orange colour. The resulting solution was evaporated to dryness to give a yellowish orange solid which was then extracted with dichloromethane (20 mL). The addition of hexane (100 mL) to this solution led to yellow needle shaped diffraction quality crystals. These were separated and washed with hexane and dried. Yield: (0.768 g, 75 %). Anal. Calc. for C36H52N2P2Au2Fe: C, 42.19; H, 5.08; N,2.73. Found: C, 42.32; H, 5.32; N, 2.94. IR (cm-1, KBr): n 3401, 2930, 2850, 2360, 2340, 2151(CN), 1730, 1440, 1240, 1164, 1110, 1032, 868, 630, 490. 1H NMR (delta ppm, 400 MHz, CDCl3, 298 K), 4.40 (s, 4H, C5H4), 4.22 (s, 4H, C5H4), 2.71-1.22 (m, 44H, Cy). 31P{1H}: delta 41.6 (s) (Sharp). UV/Vis: lambdamax (epsilon [dm3 mol-1 cm-1]) 267 (10,727), 460 (23,595). ESI-MS (m/z): 1024.1 (M+)., 146960-90-9
146960-90-9 1,1′-Bis(dicyclohexylphosphino)ferrocene 44558250, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Article; Trivedi, Manoj; Bhaskaran; Singh, Gurmeet; Kumar, Abhinav; Rath, Nigam P.; Journal of Organometallic Chemistry; vol. 758; (2014); p. 9 – 18;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate