With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-20-8,Cyclohexyldiphenylphosphine oxide,as a common compound, the synthetic route is as follows.
Add cyclohexyldiphenylphosphine (28.4 mg, 0.1 mmol), copper triflate (3.6 mg, 0.01 mmol),Tetramethyldisilazane (26.7 mg, 0.2 mmol) and toluene (1 mL), the mixture was stirred at 80oC;TLC follows the reaction to completion;The crude product obtained after the reaction was recrystallized from toluene to obtain the target product (yield 82%). The analytical data of the product are as follows:, 13689-20-8
13689-20-8 Cyclohexyldiphenylphosphine oxide 83664, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Patent; Soochow University (Suzhou); Zou Jianping; Li Chengkun; Yan Xuping; Wang Yijie; (14 pag.)CN110256489; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate