With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.
General procedure: A mixture of Ru3(CO)10(arphos) (52.3mg, 0.051mmol) and PCy3 (14.0mg, 0.051mmol) was heated in refluxing hexane (25ml) for 1h. Completion of the reaction was monitored by TLC. The solvent was removed under reduced pressure. The reaction mixture was separated by preparative TLC (2:3 dichloromethane:hexane), affording three bands. The first band (Rf=0.76) gave the starting material Ru3(CO)10(arphos), the second band (Rf=0.57) gave the major product, characterised as Ru3(CO)9(arphos)PCy3, and the third band was only obtained in trace amounts and was not characterised. The results are as follows. Yield: 21.7mg (33.28%),
18437-78-0, 18437-78-0 Tris(4-fluorophenyl)phosphine 140387, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Article; Shawkataly, Omar Bin; Sirat, Siti Syaida; Khan, Imthyaz Ahmed; Fun, Hoong-Kun; Polyhedron; vol. 63; (2013); p. 173 – 181;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate