New learning discoveries about 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

[Cu(CH3CN)4]ClO4 (16.3mg, 0.050mmol) was added to a mixture of pipH (7.4mg, 0.025mmol) and POP (26.9mg, 0.050mmol) in DCM under a stream of dry argon by using Schlenk techniques and a vacuum-line system at room temperature. A lemon-yellow solution was obtained quickly and then stirred for 2h at room temperature. After filtration through the absorbent cotton, layering n-hexane dropwise onto the dichloromethane filtrate carefully produced the target product as yellow crystals a few days later. The sample was obtained in an 84.4percent yield (35.8mg) after being dried using infrared dry technique. Anal. Calc. for C90H67Cl2Cu2N5O10P4 (1a) (1697.307): C, 63.64; H, 3.98; N, 4.12. Found: C, 63.55; H, 3.95; N, 4.12percent. ESI-MS (m/z) (see Fig. S2): 1500.35 [Cu2(pip)(POP)2]+ (calcd 1500.28); 898.195 [Cu(pipH)(POP)]+ (calcd 898.192); 601.093 [Cu(POP)]+ (calcd 601.091). 1H NMR (400MHz, DMSO-d6, delta, ppm) (see Fig. S3): 15.25 (s, 1H, NH), 9.06 (d, J=8.0Hz, 2H), 8.94 (s, 1H), 8.84 (s, 0.5H), 8.78 (d, J=8.0Hz, 1H), 8.47 (s, 1H), 8.37 (d, J=8.0Hz, 1H), 8.24 (s, 1H), 8.03 (s, 1H), 7.92 (s, 0.5H), 7.70 (s, 1H), 7.48?7.01 (m, 40H), 6.84?6.67 (m, 16H). 31P NMR (400MHz, DMSO-d6, delta, ppm): ?11.34, ?13.30, ?19.47. Characteristic IR spectrum (KBr, cm?1): 1094s (ClO4?)., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Niu, Yan-Wen; Liu, Xia; Zhao, Ling; Guo, Ya-Meng; Li, Wen-Xin; Ma, Miao-Miao; Li, Xiu-Ling; Polyhedron; vol. 157; (2019); p. 241 – 248;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate