6372-42-5, Cyclohexyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,6372-42-5
A sample of1 (0.531 g, 1.99 mmol) was dissolved in approximately 8 ml ofTHF. Cyclohexyldiphenylphosphine (1.07 g, 3.98 mmol) wasadded to the solution as a solid, causing effervescence of dinitrogen.The reaction was stirred overnight, at which pointthe volume of THF was reduced to approximately 1-2 ml toprecipitate the product. The colorless residue was filtered offon a fritted filter, rinsed with cold hexanes, and dried for 2 hunder vacuum, leading to isolation of a white powder in 60.8%yield (0.905 g). 1H NMR (CDCl3): 1.13-1.41 (m, 10H), 1.67(d, J = 12.2 Hz, 2H), 1.79 (d, J = 8.7 Hz, 4H), 1.98 (br s, 4H),2.48 (br q, J = 10.9 Hz, 2H), 4.31 (d, J = 16.4 Hz, 4H), 7.41-7.44(m, 13H), 7.56-7.81 (m, 8H), 8.01 (d, J = 7.5 Hz, 2H). 13C{1H}NMR (CDCl3): 26.19, 26.80 (d, J = 13.4 Hz), 37.29 (d, JP-C =77.0 Hz), 49.65, 123.19, 126.66, 126.87, 128.51 (d, J = 10.51 Hz),130.18, 131.01, 131.25, 132.28 (d, J = 7.7 Hz), 143.68 (d, J =18.8 Hz). 31P{1H} NMR (CDCl3): 19.41. Elemental analysiscalculated (%) for C44H49BrN2P2: C 70.68, H 3.75, N 6.61;found: C 70.68, H 3.73, N 6.56.
The synthetic route of 6372-42-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Guillet, Gary L.; Pitts, Skyler L.; Sheriff, Kirkland W.; Rucker, Donna N.; Rogers, Aaryn L.; Acta Crystallographica Section C: Structural Chemistry; vol. 75; (2019); p. 1381 – 1388;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate