With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.
1,1′-Bis(diphenylphosphino)ferrocene (dppf) (0.554 g, 1.0 mmol) was added to a solution of gold(I) cyanide (0.223 g, 1.0 mmol) in 30 mL CH3OH:CH2Cl2 (50:50 V/V) mixture at room temperature.The resultant suspension was refluxed with stirring under nitrogen atmosphere for 24 h. Slowly, the colour of the solution changed from light yellowish orange to dark yellowish orange. The resulting solution was evaporated to dryness to give a dark yellowish orange solid which were separated and washed with hexane and dried. Yield: (0.500 g, 50 percent). Anal. Calc. for C36H28N2P2Au2Fe: C, 43.20; H,2.80; N, 2.80. Found: C, 43.32; H, 2.85; N, 2.91. IR (cm-1, KBr): nu = 3430, 3022, 2929, 2147(CN), 1956, 1650, 1580, 1479, 1428, 1308, 1164, 1157, 1091, 1086, 1022, 890, 820, 740, 691, 630, 494. 1H NMR (delta ppm, 400 MHz, CDCl3, 298 K): 8.10-7.30 (m, 40H, Ph), 4.35 (s, 8H,C5H4), 4.10 (s, 8H, C5H4). 31P{1H}: delta 31.4 (s) (Sharp). UV/Vis: lambdamax (epsilon [dm3 mol-1 cm-1]) 275 (18,904), 450 (30,337). ESI-MS (m/z): 1000.8 (M+).
The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Trivedi, Manoj; Bhaskaran; Singh, Gurmeet; Kumar, Abhinav; Rath, Nigam P.; Journal of Organometallic Chemistry; vol. 758; (2014); p. 9 – 18;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate