With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.
General procedure: CuBr2 and at least four molar equivalents of the phosphine werestirred in hot ethanol under a nitrogen atmosphere. The dark reactionmixture turned gradually to colorless, with a mass of whiteprecipitation. The reaction was kept under stirring for a furthertwo hours and then left to cool down. The white precipitationwas collected by filtration, washed with a petrol/diethyl ether mixture and dried, affording the product as a white powder.
18437-78-0 Tris(4-fluorophenyl)phosphine 140387, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Article; Mashat, Khlood H.; Babgi, Bandar A.; Hussien, Mostafa A.; Nadeem Arshad, Muhammad; Abdellattif, Magda H.; Polyhedron; vol. 158; (2019); p. 164 – 172;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate