With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.
General procedure: [{Pd(mu-Cl)(kappa2N,C-C6H4CH2NMe2)}2] (500 mg, 0.91mmol) and a phosphine (1.82 mmol) were fed into a Schlenk flask under Ar atmosphere.Then, toluene (8 mL) was added to the mixture at room temperature, and the reactionmixture was stirred at 50 C overnight. The solvent was evaporated, and the resultingmass was purified by recrystallization from ether, ethanol, or pentane.
The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Rodriguez-Castanon, Jesus; Murayama, Yukako; Sano, Natsuhiro; Sanda, Fumio; Chemistry Letters; vol. 44; 9; (2015); p. 1200 – 1201;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate