With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.
Compound 3 was obtained while attempting to synthesize the tetrakis adduct. TFFPP (0.0800 g, 0.232 mmol) was added to a solution of [AuCl(C4H8S)] (0.0134 g, 0.058 mmol) in tetrahydrofuran (20 mL) at -80 ¡ãC and the reaction stirred for 2 h. The solvent was removed by purging nitrogen gas into the solution, until all the solvent dried up. The residue was then recrystallized from CH2Cl2/n-hexane mixture. After nine days partial evaporation of the solvent provided x-ray quality crystals. Yield is 94percent. 1H NMR [delta (ppm)]: 7.2(m) and 7.7(m). 31P NMR [delta (ppm)]: 81.1.
18437-78-0 Tris(4-fluorophenyl)phosphine 140387, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Article; Agbeworvi, George; Assefa, Zerihun; Sykora, Richard E.; Taylor, Jared; Crawford, Carlos; Journal of Molecular Structure; vol. 1108; (2016); p. 508 – 515;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate