With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.
General procedure: The mixture of 5mg (1 eq) of (CO)2Rh(SQ) and 3.6mg (1.04 eq) of PPh3 was dissolved in 5ml of toluene. The mixture was kept at room temperature until complete disappearance of initial (CO)2Rh(SQ) signal in EPR spectrum. Forming violet solution was degassed, frozen by liquid N2 and 1.1 eq of corresponding diphos was added under vacuum. The mixture was quickly brought to room temperature and placed into EPR cavity immediately. All of reactions were carried out without isolation of the products.
13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Article; Kozhanov; Bubnov; Teplova; Abakumov; Cherkasov; Journal of Molecular Structure; vol. 1147; (2017); p. 541 – 548;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate