50777-76-9, 2-(Diphenylphosphino)benzaldehyde is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 2-(diphenylphosphino)benzaldehyde (0.290g, 1mmol) and 2-thiophene carboxylic acid hydrazide (0.126g, 1mmol) in ethanol (20mL) were added 2?3 drops of glacial acetic acid. The resulting solution was heated under reflux over a 3h period, and then concentrated to ca. 3mL. The white crystalline precipitate was filtered off, washed with diethyl ether (2¡Á5mL), and dried under vacuo. Yield: 87percent (0.36g). Mp: 197?199¡ãC. Anal. Calcd for C24H19N2OPS: C, 69.55; H, 4.62; N, 6.76; S, 7.74. Found: C, 69.67; H, 4.58; N, 6.86; S, 7.69. IR (KBr disks, cm?1): 3195 (m, nuNH); 1685 (s, nuC=O); 1583+1474 (s, nuC=N+nuC?N). 1H NMR (400MHz, DMSO?d6, ppm): 6.83?7.50 (m, 14H, Ar H), 7.57 (t, 1H, J=6.24, Hz Ar H), 8.05 (s, 1H, Ar H), 8.15 (s, 1H, Ar H), 8.85 (d, IH, J=3.6Hz, ?CH=N), 9.13 (s, 1H, Ar H), 11.98 (s, IH, ?NH). 13C NMR (100MHz, DMSO?d6, ppm): 125.78 (Ar C), 128.91 (Ar C), 129.15 (Ar C), 129.47 (Ar C), 130.07 (Ar C), 133.30 (Ar C), 133.49 (Ar C), 134.12 (Ar C), 135.62 (Ar C), 138.25 (Ar C), 149.52 (?CH=N), 158.12 (C=O). 31P NMR (162MHz, DMSO?d6, ppm): ?17.14.
As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.
Reference£º
Article; Ramachandran; Prakash; Viswanathamurthi; Malecki; Inorganica Chimica Acta; vol. 477; (2018); p. 122 – 129;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate