719-80-2, Ethoxydiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Ethyl diphenyl phosphinite (12.6 g, 55 MMOL) is added, at 60C and under argon, to a solution of the compound of formula (37) (15.2 g, 36.6 MMOL) IN toluene (370 ml). The reaction mixture is stirred at 60C for 3 hours and then concentrated. The residue is dissolved in 10 ml of toluene, and 10 ml of hexane are added, the product precipitating out in the form of a colourless powder, which is filtered off. In that manner, 14.3 G (73 %) of the phosphine oxide (38) can be obtained. aH NMR (300 MHz, CDCI3) : 1.22 (d, J = 6.7 Hz, 6H); 3.32-3. 45 (m, 1H); 3.41 (s, 3H); 3.47 (s, 3H); 3.89 (d, J = 12.9 Hz, 2H); 6.86 (dd, J = 8.7, 8.7 Hz, 2H); 7.09 (dd, J = 8.6, 5.3 Hz, 2H); 7.27-7. 45 (m, 10H). 13C NMR (75 MHz, CDCI3) : 22.1, 30.0 (JCP = 64.8 Hz), 33.1, 33.5, 42.7, 114.1 (Jcp = 8.2 Hz), 115.5 (JCF = 21.7 Hz), 128.8 (Jcp = 11. 8 Hz), 130.9 (Jcp = 9.3 Hz), 132.1 (JCF = 8.4 Hz), 132.1 (Jcp = 2.9 Hz), 133.3, 134.7 (Jcp = 2.3 Hz), 157.3 (Jcp = 2.3 Hz), 162.9 (JCF = 249 Hz), 166.3 (Jcp = 4.6 Hz). 3’P NMR (121 MHz, CD13) : 27.7.
719-80-2 Ethoxydiphenylphosphine 69754, achiral-phosphine-ligands compound, is more and more widely used in various.
Reference£º
Patent; CIBA SPECIALTY CHEMICALS HOLDING INC.; WO2004/103977; (2004); A2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate