With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.719-80-2,Ethoxydiphenylphosphine,as a common compound, the synthetic route is as follows.
General procedure: To a solution of [Fe2(CO)6{mu-SC6H3(CH3)S}] (0.043 g,0.1 mmol) and ethyl diphenylphosphinite (0.023 g,0.1 mmol) in CH2Cl2(5 mL) was added a solution of Me3NO¡¤2H2O (0.011 g, 0.1 mmol) in MeCN (5 mL). The mixture was stirred at room temperature for 1 h and then the solvent was reduced on a rotary evaporator. The residue was subjected to TLC using CH2Cl2/petroleum ether = 1:4(v/v) as eluent. From the main red band, 0.056 g (88%) of complex 2 was obtained as a red solid. IR (CH2Cl2, cm-1):nuC?O 2048 (vs), 1991 (vs), 1937 (m). 1H NMR (500 MHz,CDCl3):7.55 (q, J = 9 Hz, 4H, PhH), 7.40-7.32 (m, 6H,PhH), 6.57 (d, J = 7.5 Hz, 1H, C6H3H),6.30 (s, 1H, C6H3H),6.17 (d, J = 7.5 Hz, 1H, C6H3H),3.92-3.83 (m, 2H, OCH2),1.93 (s, 3H, C6H3CH3),1.28 (t, J = 7 Hz, 3H, CH2CH3)ppm.31P{1H} NMR (200 MHz, CDCl3,85% H3PO4):162.12 (s)ppm. Anal. Calcd. for C26H21Fe2O6PS2:C, 49.08; H, 3.33.Found: C, 48.88; H, 3.56%.
As the paragraph descriping shows that 719-80-2 is playing an increasingly important role.
Reference£º
Article; Lin, Hui-Min; Mu, Chao; Li, Ao; Liu, Xu-Feng; Li, Yu-Long; Jiang, Zhong-Qing; Wu, Hong-Ke; Transition Metal Chemistry; vol. 44; 5; (2019); p. 491 – 498;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate