50777-76-9, 2-(Diphenylphosphino)benzaldehyde is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 1 Preparation of N,N’-bis{[2-(diphenylphosphino)phenyllmethvlenel-2,2-dimethyl-1,3-propanediamine (L-5) Under argon, a solution of 2-(diphenylphosphino)benzaldehyde (522.7 mg, 1.8 mmol) and 2,2-dimethyl-1,3-propanediamine (93.3 mg, 0.9 mmol) in toluene (15 mL) was stirred at room temperature for 15 h. Then the reaction mixture was heated at 80; C. (oil bath) for 2,5 h. Next, the solvent was removed in vacuo, and an orange solid was recovered (476.8 mg, 0.74 mmol, 82percent). 1H NMR (CD2Cl2, 400 MHz): delta 8.78 (d, J=4.6 Hz, 2H), 7.96 (dd, J=7.7, 4.1 Hz, 2H), 7.3-7.2 (m, 24H), 6.87 (dd, J=7.7, 4.1Hz, 2H), 3.19 (s, 4H), 0.69 (s, 6H). 13C NMR (CD2CL2, 100 MHz): delta 160 (d, J=20.2 Hz, CH=N), 140.3 (d, J=17.8 Hz, Carom), 137.7 (d, J=20.2 Hz, Carom), 137.4 (d, J=10.5 Hz, Carom), 134.4 (d, J=20.2 Hz, CHarom), 134.1 (d, J=20.2 Hz, CHarom), 133.7 (CHarom), 130.2 (CHarom), 129.1 (CHarom), 128.9 (d, J=7.3 Hz, CHarom), 128.4 (d, J=4.8 Hz, CHarom), 70.7 (CH2), 36.9 (C), 24.4 (CH3). 31P{1H}NMR (CD2CL2, 100 MHz): delta -12.8.
The synthetic route of 50777-76-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SAUDAN, Lionel; Dupau, Philippe; Riedhauser, Jean-Jacques; Wyss, Patrick; US2008/71098; (2008); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate