With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6224-63-1,Tri-m-tolylphosphine,as a common compound, the synthetic route is as follows.
Reaction of glyoxylic acid (1.08 g, 11.7 mmol) in dry diethyl ether (100 mL) with tris-(m-tolyl)phosphane (3.56 g, 11.7 mmol) in dry diethyl ether (20 mL) at room temperature and work up as described for 3a gave 2.18 g (49percent) of a white powder of 3b.
As the paragraph descriping shows that 6224-63-1 is playing an increasingly important role.
Reference£º
Article; Basvani, Kaleswara Rao; Fomina, Olga S.; Yakhvarov, Dmitry G.; Heinicke, Joachim; Polyhedron; vol. 67; (2014); p. 306 – 313;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate