With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.
General procedure: To a solution of 2-(diphenylphosphino)benzaldehyde (0.29 g, 1 mmol) and 4-methyl-3-thiosemicarbazide (0.10 g, 1 mmol) in ethanol (20 mL) were added 2?3 drops of glacial acetic acid. The pale yellow solution was heated under reflux over a 2 h period, and then concentrated to dryness. The resulting yellow oil was treated with diethyl ether (2 5 mL). The pale yellow precipitate was filtered off, washed with diethyl ether (10 mL) and dried under vacuo
The synthetic route of 50777-76-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Ramachandran, Rangasamy; Prakash, Govindan; Vijayan, Paranthaman; Viswanathamurthi, Periasamy; Grzegorz Malecki, Jan; Inorganica Chimica Acta; vol. 464; (2017); p. 88 – 93;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate