Bai, Yaguang; Leng, Wei Lin; Li, Yongxin; Liu, Xue-Wei published the article 《A highly efficient dual catalysis approach for C-glycosylation: addition of (o-azaaryl)carboxaldehyde to glycals》. Keywords: C glycosylation azaarylcarboxaldehyde glycals palladium heterocyclic carbene catalyst.They researched the compound: 5-Chloropicolinaldehyde( cas:31181-89-2 ).Product Details of 31181-89-2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:31181-89-2) here.
A novel and efficient dual catalysis approach by concurrent activation of glycals and (o-azaaryl)-carboxaldehydes using palladium and N-heterocyclic carbene has been developed. The two electrophiles could react after activation through formation of the Breslow intermediate and a π-allyl Pd complex, widening the scope of reacting glycosylation partners and opening up possibilities for future glycosylation.
This literature about this compound(31181-89-2)Product Details of 31181-89-2has given us a lot of inspiration, and I hope that the research on this compound(5-Chloropicolinaldehyde) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate